Yes, BUt you may have misunderstood the meaning of that term.
De-rating a circuit is done many times. But de-rating is for the total load of a panel, NOT the individual line, a breaker (fuse, etc) is there to protect the wiring from over load. An example is a 8 unit building, each unit may have a 100 amp panel, but the building set up may allow you to de-rate that to a 400 amp main panel to service the entire building, as when the units are offices, they may have 100 amp sub panels. but never need that much. it does NOT mean to use smaller wires. a 100 amp panel needs 100 amp wire, a 400 amp needs 400 amp wire. 50 amp welder plug needs a 50 amp wire and breaker, IF you have 10 gauge then its 30 amp. putting a 50 amp breaker on a 30 amp line, is removing the stated protection, and can cause you or your kid, friends, etc, to DIE.
A laundry have have 20 circuits for 30 amp dryers. While each circuit is still a 30 amp breaker, the main panel can does not need to have 600 amps. due to de-rating it can be less than a 600 amp panel, because it should never need that much. But each 30 amp line, must still be protected by a 30 amp breaker if they are wired with 10 gauge THHN wire. Just as 50 amp breakers should have at least 8 gauge THHN wiring.
Any more info and I will have to charge you :)