I just put a bag of Mesquite in today and it was terrible. I had been using home made as I have a fire pit and just quench the coals directly but ran out and a friend had brought over a large 20 lb bag of Mesquite so i used it and it threw fleas every time I raked some new coal in.
To the OP I also used a bag of cowboy just to see how it compared to my home made and there was no difference to me.